Our Science

Every active in She-Lajit Honey Sticks is named, dosed on the label, and tied to a randomized controlled trial on that ingredient in women — with the trial dose stated plainly. Where a published trial used a higher oral dose than our sublingual dose, we say so: sublingual delivery bypasses the first-pass liver loss that destroys 70–90% of a swallowed botanical, so the numbers are not meant to read as identical. We do not borrow a citation from a trial on a different formula. The primary trials below link to their PubMed or NCBI record.

Shatavari · Asparagus racemosus · 80 mg standardized

  • Pingali et al., 2024. Cureus. Double-blind, multicenter, randomized controlled trial — n=70 peri- and postmenopausal women, 250 mg twice daily (oral). Significant improvement in Utian Quality of Life scores at days 30 and 60 (p<0.0001). PubMed 38725785 →

Our dose: 80 mg standardized root extract, delivered sublingually. The trial above used a higher oral dose; we cite it to establish shatavari's effect in menopausal women, not to claim an identical effect size at our dose.

Shilajit · Asphaltum punjabianum · 300 mg purified

  • Pingali et al., 2022. Phytomedicine. Randomized, double-blind, placebo-controlled trial — n=60 postmenopausal women with osteopenia, 48 weeks, 250–500 mg/day. Dose-dependent preservation of bone mineral density at the lumbar spine and femoral neck (p<0.001). PubMed 35933897 →
  • Mosavi et al., 2023. Triple-blind, placebo-controlled RCT — n=43 reproductive-age women, 200 mg twice daily. Female Sexual Function Index improved versus placebo over 60–90 days. (Published 2023; mechanistically relevant for the post-oophorectomy cohort.)

Our dose: 300 mg purified — within the 250–500 mg/day range used in the bone-density trial.

Saffron · Crocus sativus · 2 mg standardized

  • Hausenblas et al., 2013. Journal of Integrative Medicine. Meta-analysis of 5 RCTs — saffron at 30 mg/day oral, comparable to fluoxetine for mild-to-moderate depression. PubMed 24299602 →
  • Kashani et al., 2022. Avicenna Journal of Phytomedicine. Three-center, double-blind RCT — saffron 15 mg twice daily, Female Sexual Function Index improvement. PubMed 36186931 →

The saffron rule — read this. The saffron trials above used roughly 30 mg oral. Our stick contains 2 mg, delivered sublingually. We cite this research to establish saffron's neuropharmacology — its action at TPH2, MAO-A, dopamine, and GABA — not to claim the same antidepressant effect size at 2 mg. The dose-matched, RCT-backed clinical weight in this formula rides on shilajit and shatavari.

Sublingual delivery · 8 g honey vehicle

  • StatPearls (NCBI Bookshelf), NBK557852. Sublingual oral-mucosal absorption routes compounds through the internal jugular vein into systemic circulation, bypassing first-pass hepatic metabolism — the reason a sublingual botanical can use a lower dose than its swallowed counterpart. NCBI Bookshelf →

Citations are to trials on the named ingredient in human subjects. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.